ERCC8 Protein (AA 1-397) (His tag)

Catalog No. ABIN1631891

Product Details

Target: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Protein Type: Recombinant

Protein Characteristics: AA 1-397

Origin: Cow

Source: Yeast

Purification tag / Conjugate: This ERCC8 protein is labelled with His tag.

Application: ELISA

Sequence: MLGFLSARQA GLEDPLRLRR AESTRRVLGL ELNKDRDVER IHCSGVNTLD IEPVEGRYML SGGSDGVIVL YDLENSSRQP YYTCKAVCSV GRSHPDVHKY SVETVQWYPH DTGMFTSSSF DKTLKVWDTN TLQIADVFNF EETVYSHHMS PVATKHCLVA VGTRGPKVQL CDLKSGSCSH ILQGHRQEIL AVSWSPRYEY ILATASADSR AKLWDVRRAS GCLITLDQHN GKKSQAAESA NTAHNGKVNG LCFTSDGLHL LTVGTDNRMR LWNSSNGENT LVNYGKVYND SRKGLKFTVS SGCSSEFVFV PYGSTIAVYT IYSGEQITML KGHYKSVDCC VFQSNFQELY SGSRDCNILA WVPSLCESVP DDDDETSTRS QLNPAFEDAW SSSDEEG

Specificity: Bos taurus (Bovine)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Alternative Name: DNA excision repair protein ERCC-8 (ERCC8) (ERCC8 Products)

Synonyms: zgc:103550 Protein, CKN1 Protein, CSA Protein, UVSS2 Protein, Ckn1 Protein, 2410022P04Rik Protein, 2810431L23Rik Protein, 4631412O06Rik Protein, B130065P18Rik Protein, Csa Protein, excision repair cross-complementation group 8 Protein, ERCC excision repair 8, CSA ubiquitin ligase complex subunit Protein, excision repaiross-complementing rodent repair deficiency, complementation group 8 Protein, ercc8 Protein, ERCC8 Protein, Ercc8 Protein

Background: Recommended name: DNA excision repair protein ERCC-8

UniProt: Q5BIM8

Pathways: DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus