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LAIR2 Protein (AA 22-152) (His tag)

LAIR2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691101
  • Target See all LAIR2 Proteins
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-152
    Origin
    Human
    Source
    • 9
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This LAIR2 protein is labelled with His tag.
    Purpose
    Recombinant Human LAIR-2/CD306 (C-6His)
    Sequence
    QEGALPRPSI SAEPGTVISP GSHVTFMCRG PVGVQTFRLE REDRAKYKDS YNVFRLGPSE SEARFHIDSV SEGNAGLYRC LYYKPPGWSE HSDFLELLVK ESSGGPDSPD TEPGSSAGTV PGTEASGFDA PVDHHHHHH
    Characteristics
    Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2/LAIR2 produced by transfected human cells is a secreted protein with sequence (Gln22-Pro152) of Human LAIR2 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product LAIR2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    Alternative Name
    lair2 (LAIR2 Products)
    Synonyms
    CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
    Sub Type
    Fusionprotein
    Background
    Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% amino acid identity across the signal sequence and extracellular domains, although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.
    Alternative Names: Leukocyte-Associated Immunoglobulin-Like Receptor 2, LAIR-2, CD306, LAIR2
    Molecular Weight
    15.1 kDa
    UniProt
    Q6ISS4
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