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SEMG1 Protein (AA 24-402) (His tag)

SEMG1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691306
  • Target See all SEMG1 Proteins
    SEMG1 (Semenogelin I (SEMG1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-402
    Origin
    • 6
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This SEMG1 protein is labelled with His tag.
    Purpose
    Recombinant Human Semenogelin-1/SEMG1 (C-6His)
    Sequence
    QKGGSKGRLP SEFSQFPHGQ KGQHYSGQKG KQQTESKGSF SIQYTYHVDA NDHDQSRKSQ QYDLNALHKT TKSQRHLGGS QQLLHNKQEG RDHDKSKGHF HRVVIHHKGG KAHRGTQNPS QDQGNSPSGK GISSQYSNTE ERLWVHGLSK EQTSVSGAQK GRKQGGSQSS YVLQTEELVA NKQQRETKNS HQNKGHYQNV VEVREEHSSK VQTSLCPAHQ DKLQHGSKDI FSTQDELLVY NKNQHQTKNL NQDQQHGRKA NKISYQSSST EERRLHYGEN GVQKDVSQRS IYSQTEKLVA GKSQIQAPNP KQEPWHGENA KGESGQSTNR EQDLLSHEQK GRHQHGSHGG LDIVIIEQED DSDRHLAQHL NNDQNPLFTV DHHHHHH
    Characteristics
    Recombinant Human Semenogelin-1/SEMG1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln24-Thr402) of Human SEMG1 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SEMG1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Hac-NaAc, 150 mM NaCl, pH 4.5.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    SEMG1 (Semenogelin I (SEMG1))
    Alternative Name
    semg1 (SEMG1 Products)
    Synonyms
    SEMG1 Protein, SEMG1a Protein, CT103 Protein, SEMG Protein, SGI Protein, dJ172H20.2 Protein, RATSVPIIA Protein, SVPIIA Protein, SVS2P Protein, Svp1 Protein, Svs2 Protein, Svs2p2 Protein, BB115391 Protein, Semg1 Protein, SvsII Protein, semenogelin II Protein, semenogelin I Protein, semenogelin-2 Protein, seminal vesicle secretory protein 2 Protein, SEMG2 Protein, SEMG1 Protein, LOC100408385 Protein, Semg1 Protein, Svs2 Protein
    Sub Type
    Fusionprotein
    Background
    Semenogelin-1 (SEMG1) is the predominant protein in semen, it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced, they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks down the gel matrix, allowing the spermatozoa to move more freely.
    Alternative Names: Semenogelin-1, Semenogelin I, SGI, SEMG1, SEMG, Alpha-Inhibin-92, Alpha-Inhibin-31, Seminal Basic Protein
    Molecular Weight
    43.8 kDa
    UniProt
    P04279
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