SGSH Protein (AA 21-502) (His tag)
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- Target See all SGSH Proteins
- SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-502
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SGSH protein is labelled with His tag.
- Purpose
- Recombinant Human N-Sulphoglucosamine Sulphohydrolase/SGSH (C-6His)
- Sequence
- RPRNALLLLA DDGGFESGAY NNSAIATPHL DALARRSLLF RNAFTSVSSC SPSRASLLTG LPQHQNGMYG LHQDVHHFNS FDKVRSLPLL LSQAGVRTGI IGKKHVGPET VYPFDFAYTE ENGSVLQVGR NITRIKLLVR KFLQTQDDRP FFLYVAFHDP HRCGHSQPQY GTFCEKFGNG ESGMGRIPDW TPQAYDPLDV LVPYFVPNTP AARADLAAQY TTVGRMDQGV GLVLQELRDA GVLNDTLVIF TSDNGIPFPS GRTNLYWPGT AEPLLVSSPE HPKRWGQVSE AYVSLLDLTP TILDWFSIPY PSYAIFGSKT IHLTGRSLLP ALEAEPLWAT VFGSQSHHEV TMSYPMRSVQ HRHFRLVHNL NFKMPFPIDQ DFYVSPTFQD LLNRTTAGQP TGWYKDLRHY YYRARWELYD RSRDPHETQN LATDPRFAQL LEMLRDQLAK WQWETHDPWV CAPDGVLEEK LSPQCQPLHN ELVDHHHHHH
- Characteristics
- Recombinant Human N-Sulphoglucosamine Sulphohydrolase/SGSH is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg21-Leu502) of Human SGSH fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SGSH Protein
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N-Sulfoglucosamine Sulfohydrolase (SGSH) (AA 1-502) protein (GST tag)
SGSH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
N-Sulfoglucosamine Sulfohydrolase (SGSH) (AA 21-502) protein (His tag)Crystallography grade SGSH Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
N-Sulfoglucosamine Sulfohydrolase (SGSH) protein (Myc-DYKDDDDK Tag)SGSH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
- Abstract
- SGSH Products
- Synonyms
- HSS Protein, MPS3A Protein, SFMD Protein, 4632406A19Rik Protein, N-sulfoglucosamine sulfohydrolase Protein, N-sulfoglucosamine sulfohydrolase (sulfamidase) Protein, SGSH Protein, Sgsh Protein
- Sub Type
- Fusionprotein
- Background
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N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
Alternative Names: N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS - Molecular Weight
- 55.72 kDa
- UniProt
- P51688
- Pathways
- Glycosaminoglycan Metabolic Process
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