PPID Protein (AA 2-370) (His tag)

Catalog No. ABIN1691909

Product Details

Target: PPID (Peptidylprolyl Isomerase D (PPID))

Protein Type: Recombinant

Protein Characteristics: AA 2-370

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PPID protein is labelled with His tag.

Purpose: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase D/PPID/PPIase D (N, C-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MSHPSPQAKP SNPSNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGIGH TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM ANAGRNTNGS QFFITTVPTP HLDGKHVVFG QVIKGIGVAR ILENVEVKGE KPAKLCVIAE CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LITEDLKNIG NTFFKSQNWE MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK EKAVYAKMFA VEHHHHHH

Characteristics: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase D/PPID is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Ala370) of Human PPID fused with a 6His tag at both the N-terminus and C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: PPID (Peptidylprolyl Isomerase D (PPID))

Alternative Name: PPID (PPID Products)

Synonyms: PPID Protein, CYP-40 Protein, CYPD Protein, Cyp-40 Protein, CypD Protein, wu:fb18b07 Protein, zgc:86711 Protein, 4930564J03Rik Protein, Ppidl Protein, Ppif Protein, cyp-40 Protein, cypd Protein, peptidylprolyl isomerase D Protein, peptidylprolyl isomerase D (cyclophilin D) Protein, peptidylprolyl isomerase D (cyclophilin D) S homeolog Protein, PPID Protein, Ppid Protein, ppid Protein, ppid.S Protein

Sub Type: Fusionprotein

Background: Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
Alternative Names: Peptidyl-Prolyl Cis-Trans Isomerase D, PPIase D, 40 kDa Peptidyl-Prolyl Cis-Trans Isomerase, Cyclophilin-40, CYP-40, Cyclophilin-Related Protein, Rotamase D, PPID, CYP40, CYPD

Molecular Weight: 43.9 kDa

UniProt: Q08752

Pathways: Nuclear Hormone Receptor Binding