PHLDA2 Protein (AA 1-152) (His tag)

Catalog No. ABIN1692073

Product Details

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Protein Type: Recombinant

Protein Characteristics: AA 1-152

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PHLDA2 protein is labelled with His tag.

Purpose: Recombinant Human PH-Like Domain A2/PHLDA2/BWR1C/IPL/TSSC3 (C-6His)

Sequence: MKSPDEVLRE GELEKRSDSL FQLWKKKRGV LTSDRLSLFP ASPRARPKEL RFHSILKVDC VERTGKYVYF TIVTTDHKEI DFRCAGESCW NAAIALALID FQNRRALQDF RSRQERTAPA APAEDAVAAA AAAPSEPSEP SRPSPQPKPR TPLEHHHHHH

Characteristics:

Recombinant Human PH-Like Domain A2/PHLDA2/BWR1C/IPL/TSSC3 (C-6His)

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 0.1M NaCl, 1 mM DTT, pH 8.0.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Alternative Name: Pleckstrin Homology-Like Domain Family A Member 2/PHLDA2 (PHLDA2 Products)

Synonyms: PHLDA2 Protein, ipl Protein, phlda2 Protein, BRW1C Protein, BWR1C Protein, HLDA2 Protein, IPL Protein, TSSC3 Protein, Ipl Protein, Tssc3 Protein, zgc:110459 Protein, pleckstrin homology like domain family A member 2 Protein, Pleckstrin homology-like domain family A member 2 Protein, pleckstrin homology like domain, family A, member 2 Protein, pleckstrin homology-like domain, family A, member 2 Protein, pleckstrin homology-like domain, family A, member 2 L homeolog Protein, PHLDA2 Protein, phla2 Protein, Phlda2 Protein, phlda2.L Protein, phlda2 Protein

Background: Recombinant Human Pleckstrin Homology-Like Domain Family A Member 2/PHLDA2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro152) of Human PHLDA2 fused with a 6His tag at the C-terminus.
Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present in all cells of the villous cytotrophoblast. PHLDA2 plays a role in regulating placenta growth. PHLDA2 may act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.

Molecular Weight: 18.1 kDa

UniProt: Q53GA4

Pathways: Regulation of Carbohydrate Metabolic Process