MYOZ2 Protein (AA 1-264) (His tag)

Catalog No. ABIN1692265

Product Details

Target: MYOZ2 (Myozenin 2 (MYOZ2))

Protein Type: Recombinant

Protein Characteristics: AA 1-264

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MYOZ2 protein is labelled with His tag.

Purpose: Recombinant Human Myozenin-2/MYOZ2 (C-6His)

Sequence: MLSHNTMMKQ RKQQATAIMK EVHGNDVDGM DLGKKVSIPR DIMLEELSHL SNRGARLFKM RQRRSDKYTF ENFQYQSRAQ INHSIAMQNG KVDGSNLEGG SQQAPLTPPN TPDPRSPPNP DNIAPGYSGP LKEIPPEKFN TTAVPKYYQS PWEQAISNDP ELLEALYPKL FKPEGKAELP DYRSFNRVAT PFGGFEKASR MVKFKVPDFE LLLLTDPRFM SFVNPLSGRR SFNRTPKGWI SENIPIVITT EPTDDTTVPE SEDLLEHHHH HH

Characteristics: Recombinant Human Myozenin-2/MYOZ2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu264) of Human MYOZ2 fused with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 10 mM Tris, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: MYOZ2 (Myozenin 2 (MYOZ2))

Alternative Name: MYOZ2 (MYOZ2 Products)

Synonyms: LOC733663 Protein, myoz2 Protein, MGC52797 Protein, cs-1 Protein, myozenin-2 Protein, MYOZ2 Protein, Myozenin-2 Protein, DKFZp468M0519 Protein, 1110012I24Rik Protein, Fatz-2 Protein, Myozl2 Protein, C4orf5 Protein, CMH16 Protein, CS-1 Protein, myozenin 2 Protein, myozenin 2 S homeolog Protein, myozenin 2 L homeolog Protein, MYOZ2 Protein, myoz2.S Protein, myoz2.L Protein, myoz2 Protein, Myoz2 Protein

Sub Type: Fusionprotein

Background: Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder.
Alternative Names: Myozenin-2, Calsarcin-1, FATZ-Related Protein 2, MYOZ2, C4orf5

Molecular Weight: 30.9 kDa

UniProt: Q9NPC6