Tachykinin 3 Protein (TAC3) (AA 17-121) (His tag)

Catalog No. ABIN1692329

Product Details

Target: Tachykinin 3 (TAC3)

Protein Type: Recombinant

Protein Characteristics: AA 17-121

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Tachykinin 3 protein is labelled with His tag.

Purpose: Recombinant Human Tachykinin-3/TAC3 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MQSFGAVCKE PQEEVVPGGG RSKRDPDLYQ LLQRLFKSHS SLEGLLKALS QASTDPKEST SPEKRDMHDF FVGLMGKRSV QPDSPTDVNQ ENVPSFGILK YPPRAE

Characteristics: Recombinant Human Tachykinin-3/TAC3 is produced with our E. coli expression system. The target protein is expressed with sequence (Gln17-Glu121) of Human TAC3 fused with a His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Tachykinin 3 (TAC3)

Alternative Name: TAC3 (TAC3 Products)

Synonyms: TAC3 Protein, NKB Protein, PPT-B Protein, Tac3 Protein, HH10 Protein, NKNB Protein, PRO1155 Protein, ZNEUROK1 Protein, Tac2 Protein, tachykinin 3 Protein, tachykinin 2 Protein, TAC3 Protein, Tac2 Protein, Tac3 Protein

Sub Type: Fusionprotein

Background: Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses, they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. TAC3 acts as the ligand for the neurokinin-3 receptor, mutations in this gene are associated with normosmic hypogonadotropic hypogonadism.
Alternative Names: Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB, UNQ585/PRO1155

Molecular Weight: 13.9 kDa

UniProt: Q9UHF0