PIN4 Protein (AA 1-156) (His tag)
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- Target See all PIN4 Proteins
- PIN4 (Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-156
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PIN4 protein is labelled with His tag.
- Purpose
- Recombinant Human Parvulin-14/PIN4 (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MPMAGLLKGL VRQLEQFRVQ QQASKMPPKG KSGSGKAGKG GAASGSDSAD KKAQGPKGGG NAVKVRHILC EKHGKIMEAM EKLKSGMRFN EVAAQYSEDK ARQGGDLGWM TRGSMVGPFQ EAAFALPVSG MDKPVFTDPP VKTKFGYHII MVEGRK
- Characteristics
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Recombinant Human Parvulin-14/PIN4 (N-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PIN4 Protein
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Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4) (AA 1-156) protein (His tag)
PIN4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4) (AA 1-131) protein (His-IF2DI Tag)PIN4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4) (AA 1-156) protein (GST tag)PIN4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4) (AA 61-156) protein (GST tag)PIN4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4) (AA 1-131) protein (Strep Tag)Crystallography grade PIN4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4) (AA 1-131) protein (Strep Tag)Crystallography grade PIN4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- PIN4 (Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting 4 Protein (PIN4))
- Alternative Name
- Parvulin-14/PIN4 (PIN4 Products)
- Synonyms
- 2410002I22Rik Protein, EPVH Protein, Par14 Protein, PAR14 Protein, PAR17 Protein, zgc:110008 Protein, peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Protein, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) Protein, protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) Protein, PIN4 Protein, Pin4 Protein, pin4 Protein
- Background
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Recombinant Human Parvulin-14/PIN4 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys156) of Human PIN4 fused with a 6His tag at the N-terminus.
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA. - Molecular Weight
- 18.8 kDa
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