FKBP4 Protein (AA 1-459) (His tag)
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- Target See all FKBP4 Proteins
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-459
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FKBP4 protein is labelled with His tag.
- Purpose
- Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP4/FKBP4 (C-6His)
- Sequence
- MTAEEMKATE SGAQSAPLPM EGVDISPKQD EGVLKVIKRE GTGTEMPMIG DRVFVHYTGW LLDGTKFDSS LDRKDKFSFD LGKGEVIKAW DIAIATMKVG EVCHITCKPE YAYGSAGSPP KIPPNATLVF EVELFEFKGE DLTEEEDGGI IRRIQTRGEG YAKPNEGAIV EVALEGYYKD KLFDQRELRF EIGEGENLDL PYGLERAIQR MEKGEHSIVY LKPSYAFGSV GKEKFQIPPN AELKYELHLK SFEKAKESWE MNSEEKLEQS TIVKERGTVY FKEGKYKQAL LQYKKIVSWL EYESSFSNEE AQKAQALRLA SHLNLAMCHL KLQAFSAAIE SCNKALELDS NNEKGLFRRG EAHLAVNDFE LARADFQKVL QLYPNNKAAK TQLAVCQQRI RRQLAREKKL YANMFERLAE EENKAKAEAS SGDHPTDTEM KEEQKSNTAG SQSQVETEAL EHHHHHH
- Characteristics
- Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP4/FKBP4 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala459) of Human FKBP4 fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FKBP4 Protein
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FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (GST tag)
FKBP4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) (Active) protein (His tag)FKBP4 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 301-410) protein (GST tag)FKBP4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (His tag)FKBP4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (Strep Tag)Crystallography grade FKBP4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 2-459) protein (His tag)Crystallography grade FKBP4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-458) protein (Strep Tag)Crystallography grade FKBP4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
FK506 Binding Protein 4, 59kDa (FKBP4) (AA 2-458) protein (His tag)Crystallography grade FKBP4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,10 % glycerol, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- Alternative Name
- FKBP4 (FKBP4 Products)
- Synonyms
- HBI Protein, p52 Protein, hsp56 Protein, PPIase Protein, fkbp52 Protein, fkbp59 Protein, MGC81078 Protein, wu:fb34f09 Protein, 59kDa Protein, AL022792 Protein, AW208983 Protein, FKBP-4 Protein, FKBP-52 Protein, FKBP52 Protein, FKPB52 Protein, p59 Protein, FKBP51 Protein, FKBP59 Protein, Hsp56 Protein, P59 Protein, FK506 binding protein 4 Protein, FK506 binding protein 4 S homeolog Protein, FKBP4 Protein, fkbp4.S Protein, fkbp4 Protein, Fkbp4 Protein
- Sub Type
- Fusionprotein
- Background
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FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP4, 51kDa FK506-binding protein, 51kDa FK506-binding protein, 59kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4 - Molecular Weight
- 52.8 kDa
- UniProt
- Q02790
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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