NHP2 Protein (AA 1-153) (His tag)
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- Target See all NHP2 Proteins
- NHP2 (NHP2 Ribonucleoprotein (NHP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-153
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NHP2 protein is labelled with His tag.
- Purpose
- Recombinant Human Nucleolar Protein Family A Member 2/NHP2/NOLA2 (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MTKIKADPDG PEAQAEACSG ERTYQELLVN QNPIAQPLAS RRLTRKLYKC IKKAVKQKQI RRGVKEVQKF VNKGEKGIMV LAGDTLPIEV YCHLPVMCED RNLPYVYIPS KTDLGAAAGS KRPTCVIMVK PHEEYQEAYD ECLEEVQSLP LPL
- Characteristics
- Recombinant Human Nucleolar protein family A member 2/NHP2/NOLA2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu153) of Human NHP2 fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product NHP2 Protein
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NHP2 Ribonucleoprotein (NHP2) (AA 1-153) protein (His tag)
NHP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
NHP2 Ribonucleoprotein (NHP2) (AA 1-153) protein (GST tag)NHP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
NHP2 Ribonucleoprotein (NHP2) (AA 54-153) protein (GST tag)NHP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
NHP2 Ribonucleoprotein (NHP2) (AA 1-153) protein (Strep Tag)Crystallography grade NHP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
NHP2 Ribonucleoprotein (NHP2) (AA 1-153) protein (Strep Tag)Crystallography grade NHP2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT, pH 8.0.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- NHP2 (NHP2 Ribonucleoprotein (NHP2))
- Alternative Name
- Nucleolar Protein Family A Member 2/NHP2/NOLA2 (NHP2 Products)
- Synonyms
- DKCB2 Protein, NHP2P Protein, NOLA2 Protein, 2410130M07Rik Protein, D11Ertd175e Protein, Nola2 Protein, NHP2 ribonucleoprotein Protein, NHP2 Protein, Nhp2 Protein
- Sub Type
- Fusionprotein
- Background
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NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Alternative Names: H/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2, NHP2, NOLA2, NHP2P. - Molecular Weight
- 19.3 kDa
- UniProt
- Q9NX24
- Pathways
- Telomere Maintenance
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