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Alkaline Phosphatase Protein (ALP) (AA 23-506) (His tag)

ALP Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1880492
  • Target See all Alkaline Phosphatase (ALP) products
    Alkaline Phosphatase (ALP)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-506
    Origin
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Alkaline Phosphatase protein is labelled with His tag.
    Purpose
    Recombinant Human Alkaline Phosphatase/ALPP/PLAP (C-6His)
    Sequence
    IIPVEEENPD FWNREAAEAL GAAKKLQPAQ TAAKNLIIFL GDGMGVSTVT AARILKGQKK DKLGPEIPLA MDRFPYVALS KTYNVDKHVP DSGATATAYL CGVKGNFQTI GLSAAARFNQ CNTTRGNEVI SVMNRAKKAG KSVGVVTTTR VQHASPAGTY AHTVNRNWYS DADVPASARQ EGCQDIATQL ISNMDIDVIL GGGRKYMFRM GTPDPEYPDD YSQGGTRLDG KNLVQEWLAK RQGARYVWNR TELMQASLDP SVTHLMGLFE PGDMKYEIHR DSTLDPSLME MTEAALRLLS RNPRGFFLFV EGGRIDHGHH ESRAYRALTE TIMFDDAIER AGQLTSEEDT LSLVTADHSH VFSFGGYPLR GSSIFGLAPG KARDRKAYTV LLYGNGPGYV LKDGARPDVT ESESGSPEYR QQSAVPLDEE THAGEDVAVF ARGPQAHLVH GVQEQTFIAH VMAFAACLEP YTACDLAPPA GTTDVDHHHH HH
    Characteristics
    Recombinant Human Alkaline Phosphatase/ALPP/PLAP is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ile23-Asp506) of Human ALPP fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 .
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Alkaline Phosphatase (ALP)
    Alternative Name
    Alkaline Phosphatase (ALP Products)
    Synonyms
    ALP Protein, ALP1 Protein, CRASH Protein, ECK0378 Protein, JW0374 Protein, psiA Protein, 2410004D18Rik Protein, AU040643 Protein, AW060375 Protein, ILC Protein, CTACK Protein, ESkine Protein, Akp2 Protein, alp Protein, zgc:56672 Protein, DDBDRAFT_0205491 Protein, DDBDRAFT_0231570 Protein, DDB_0205491 Protein, DDB_0231570 Protein, Actn2lp Protein, Alp Protein, asparaginase like 1 Protein, bacterial alkaline phosphatase Protein, C-C motif chemokine ligand 27 Protein, alkaline phosphatase, liver/bone/kidney Protein, alkaline phosphatase Protein, PDZ and LIM domain 3 Protein, ASRGL1 Protein, phoA Protein, Asrgl1 Protein, CCL27 Protein, alpl Protein, alp Protein, Pdlim3 Protein
    Sub Type
    Fusionprotein
    Background
    ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.
    Alternative Names: Alkaline phosphatase, placental type, also known as Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, ALPP and PLAP, belongs to the alkaline phosphatase family.
    Molecular Weight
    53.7 kDa
    UniProt
    P05187
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