XCL1 Protein (AA 22-114) (Fc Tag,His tag)

Catalog No. ABIN1880519

Product Details

Target: XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))

Protein Type: Recombinant

Protein Characteristics: AA 22-114

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This XCL1 protein is labelled with Fc Tag,His tag.

Purpose: Recombinant Human Lymphotactin/LTN/XCL1 (C-Fc-6His)

Sequence: VGSEVSDKRT CVSLTTQRLP VSRIKTYTIT EGSLRAVIFI TKRGLKVCAD PQATWVRDVV RSMDRKSNTR NNMIQTKPTG TQQSTNTAVT LTGVDDIEGR MDEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH

Characteristics: Recombinant Human Lymphotactin/LTN/XCL1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Val22-Gly114) of Human XCL1 fused with a polyhistidine tag and FC tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))

Alternative Name: XCL1 (XCL1 Products)

Synonyms: ATAC Protein, LPTN Protein, LTN Protein, SCM-1 Protein, SCM-1a Protein, SCM1 Protein, SCM1A Protein, SCYC1 Protein, AI661682 Protein, Lptn Protein, Scyc1 Protein, Ltn Protein, XCL1 Protein, XCL2 Protein, X-C motif chemokine ligand 1 Protein, chemokine (C motif) ligand 1 Protein, cytokine SCM-1 beta Protein, lymphotactin Protein, XCL1 Protein, Xcl1 Protein, LOC490356 Protein, LOC100714756 Protein, LOC100349255 Protein

Sub Type: Fusionprotein

Background: Lymphotactin, also known as ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, LTN, SCYC1 and XCL1, is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine called XCL2.
Alternative Names: Lymphotactin, ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, LTN, SCYC1 and XCL1,

Molecular Weight: 40.4 kDa

UniProt: P47992

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation