Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL2RG Protein (AA 23-262) (His tag,Fc Tag)

IL2RG Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1880619
  • Target See all IL2RG Proteins
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-262
    Origin
    • 17
    • 10
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This IL2RG protein is labelled with His tag,Fc Tag.
    Purpose
    Recombinant Human IL-2 Receptor Subunit γ/IL-2RG/CD132 (C-Fc-6His)
    Sequence
    LNTTILTPNG NEDTTADFFL TTMPTDSLSV STLPLPEVQC FVFNVEYMNC TWNSSSEPQP TNLTLHYWYK NSDNDKVQKC SHYLFSEEIT SGCQLQKKEI HLYQTFVVQL QDPREPRRQA TQMLKLQNLV IPWAPENLTL HKLSESQLEL NWNNRFLNHC LEHLVQYRTD WDHSWTEQSV DYRHKFSLPS VDGQKRYTFR VRSRFNPLCG SAQHWSEWSH PIHWGSNTSK ENPFLFALEA VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH
    Characteristics
    Recombinant Human Cytokine receptor common subunit gamma/ IL2RG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu23-Ala262) of Human IL2RG fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IL2RG Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    6 months
  • Target
    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
    Alternative Name
    IL2RG (IL2RG Products)
    Synonyms
    Ab2-183 Protein, Cd132 Protein, CD132 Protein, CIDX Protein, IL-2RG Protein, IMD4 Protein, P64 Protein, SCIDX Protein, SCIDX1 Protein, [g]c Protein, gamma(c) Protein, gc Protein, interleukin 2 receptor subunit gamma Protein, interleukin 2 receptor subunit gamma L homeolog Protein, interleukin 2 receptor, gamma chain Protein, IL2RG Protein, il2rg.L Protein, Il2rg Protein
    Sub Type
    Fusionprotein
    Background
    IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
    Alternative Names: Cytokine receptor common subunit gamma, also known as Interleukin-2 receptor subunit gamma, gammaC, P64, CD132 and IL2RG, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.
    Molecular Weight
    29.3kDa
    UniProt
    P31785
    Pathways
    JAK-STAT Signaling, Growth Factor Binding
You are here:
Support