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BPI Protein (AA 32-487) (His tag)

BPI Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1880664
  • Target See all BPI Proteins
    BPI (Bactericidal/Permeability Increasing Protein (BPI))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 32-487
    Origin
    • 7
    • 2
    • 2
    • 2
    • 1
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This BPI protein is labelled with His tag.
    Purpose
    Recombinant Human Bactericidal Permeability-Increasing Protein/BPI/CAP57 (C-6His)
    Sequence
    VNPGVVVRIS QKGLDYASQQ GTAALQKELK RIKIPDYSDS FKIKHLGKGH YSFYSMDIRE FQLPSSQISM VPNVGLKFSI SNANIKISGK WKAQKRFLKM SGNFDLSIEG MSISADLKLG SNPTSGKPTI TCSSCSSHIN SVHVHISKSK VGWLIQLFHK KIESALRNKM NSQVCEKVTN SVSSKLQPYF QTLPVMTKID SVAGINYGLV APPATTAETL DVQMKGEFYS ENHHNPPPFA PPVMEFPAAH DRMVYLGLSD YFFNTAGLVY QEAGVLKMTL RDDMIPKESK FRLTTKFFGT FLPEVAKKFP NMKIQIHVSA STPPHLSVQP TGLTFYPAVD VQAFAVLPNS SLASLFLIGM HTTGSMEVSA ESNRLVGELK LDRLLLELKH SNIGPFPVEL LQDIMNYIVP ILVLPRVNEK LQKGFPLPTP ARVQLYNVVL QPHQNFLLFG ADVVYKVDHH HHHH
    Characteristics
    Recombinant Human Bactericidal permeability-increasing protein/BPI/CAP57 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Val32-Lys487) of Human BPI fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product BPI Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    BPI (Bactericidal/Permeability Increasing Protein (BPI))
    Alternative Name
    BPI (BPI Products)
    Synonyms
    9230105K17Rik Protein, Bpifd1 Protein, BPIFD1 Protein, rBPI Protein, bpi Protein, bpi.L Protein, lbp Protein, bactericidal/permeability-increasing protein Protein, bactericidal permeablility increasing protein Protein, bactericidal/permeability-increasing protein S homeolog Protein, BPI Protein, Bpi Protein, bpi.S Protein
    Sub Type
    Fusionprotein
    Background
    Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.
    Alternative Names: Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family.
    Molecular Weight
    52.5 kDa
    UniProt
    P17213
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