IFNA4 Protein (AA 24-189) (His tag)
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- Target See all IFNA4 (IFNa4) Proteins
- IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-189
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This IFNA4 protein is labelled with His tag.
- Purpose
- Recombinant Human Interferon α-4/IFNA4 (C-6His)
- Sequence
- CDLPQTHSLG NRRALILLAQ MGRISHFSCL KDRHDFGFPE EEFDGHQFQK TQAISVLHEM IQQTFNLFST EDSSAAWEQS LLEKFSTELY QQLNDLEACV IQEVGVEETP LMNEDSILAV RKYFQRITLY LTEKKYSPCA WEVVRAEIMR SLSFSTNLQK RLRRKDVDHH HHHH
- Characteristics
- Recombinant Human Interferon alpha-4/IFNA4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Cys24-Asp189) of Human IFNA4 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IFNa4 Protein
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Interferon, alpha 4 (IFNa4) (Active) protein
IFNa4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interferon, alpha 4 (IFNa4) (AA 1-189) protein (GST tag)IFNa4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon, alpha 4 (IFNa4) (AA 24-189) protein (His tag)Crystallography grade IFNa4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon, alpha 4 (IFNa4) (AA 25-186) protein (His tag)Crystallography grade IFNa4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- IFNA4 (IFNa4) (Interferon, alpha 4 (IFNa4))
- Alternative Name
- Interferon alpha-4/IFNA4 (IFNa4 Products)
- Synonyms
- IFN-alpha4a Protein, INFA4 Protein, Ifa4 Protein, interferon alpha 4 Protein, interferon, alpha 4 Protein, interferon-alpha-4 Protein, IFNA4 Protein, Ifna4 Protein, LOC100052921 Protein
- Sub Type
- Fusionprotein
- Background
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Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
Alternative Names: Interferon alpha-4(IFNA4), also known as Interferon alpha-4B, Interferon alpha-76 and Interferon alpha-M1, belongs to the alpha/beta interferon family. - Molecular Weight
- 20.4 kDa
- UniProt
- P05014
- Pathways
- JAK-STAT Signaling, Hepatitis C
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