L-Selectin Protein (AA 39-332) (His tag)

Catalog No. ABIN1945289

Product Details

Target: L-Selectin (SELL) (Selectin L (SELL))

Protein Type: Recombinant

Protein Characteristics: AA 39-332

Origin: Chemical

Source: Human Cells

Purification tag / Conjugate: This L-Selectin protein is labelled with His tag.

Purpose: Recombinant Mouse L-Selectin/CD62L (C-6His)

Sequence: WTYHYSEKPM NWENARKFCK QNYTDLVAIQ NKREIEYLEN TLPKSPYYYW IGIRKIGKMW TWVGTNKTLT KEAENWGAGE PNNKKSKEDC VEIYIKRERD SGKWNDDACH KRKAALCYTA SCQPGSCNGR GECVETINNH TCICDAGYYG PQCQYVVQCE PLEAPELGTM DCIHPLGNFS FQSKCAFNCS EGRELLGTAE TQCGASGNWS SPEPICQVVQ CEPLEAPELG TMDCIHPLGN FSFQSKCAFN CSEGRELLGT AETQCGASGN WSSPEPICQE TNRSFSKIKE GDYNVDHHHH HH

Characteristics: Recombinant Human SELL is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 39-332) of Human SELL fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: L-Selectin (SELL Products)

Synonyms: CD62L Protein, LAM1 Protein, LECAM1 Protein, LEU8 Protein, LNHR Protein, LSEL Protein, LYAM1 Protein, PLNHR Protein, TQ1 Protein, A.11 Protein, L-selectin Protein, LECAM-1 Protein, SELE Protein, AI528707 Protein, Lnhr Protein, Ly-22 Protein, Ly-m22 Protein, Lyam-1 Protein, Lyam1 Protein, selectin L Protein, selectin, lymphocyte Protein, SELL Protein, Sell Protein

Background: L-Selectin is a member of a family of Selectin that is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes and mediates a number of leukocyte-endothelial interactions, including the binding of lymphocytes to HEV of peripheral lymph node high endothelial venules (HEV), neutrophil rolling, and leukocyte attachment to cytokine-treated endothelium in vitro.

Molecular Weight: 34.1 kDa

UniProt: P18337