SELPLG Protein (AA 42-307) (Fc Tag)

Catalog No. ABIN1945375

Product Details

Target: SELPLG (Selectin P Ligand (SELPLG))

Protein Type: Recombinant

Protein Characteristics: AA 42-307

Origin: Mouse

Source: Human Cells

Purification tag / Conjugate: This SELPLG protein is labelled with Fc Tag.

Purpose: Recombinant Mouse P-Selectin Glycoprotein Ligand 1/PSGL-1/CD162 (C-Fc)

Sequence: QVVGDDDFED PDYTYNTDPP ELLKNVTNTV AAHPELPTTV VMLERDSTSA GTSERATEKI ATTDPTAPGT GGTAVGMLST DSATQWSLTS VETVQPASTE VETSQPAPME AETSQPAPME AETSQPAPME ADTSKPAPTE AETSKPAPTE AETSQPAPNE AETSKPAPTE AETSKPAPTE AETTQLPRIQ AVKTLFTTSA ATEVPSTEPT TMETASTESN ESTIFLGPSV THLPDSGLKK GLIVTPGNSP APTLPGSSDL IPVKQCVDDI EGRMDEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK

Characteristics: Recombinant Mouse SELPLG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 42-307) of Mouse SELPLG fused with a FC tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: SELPLG (SELPLG Products)

Synonyms: CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein

Background: P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.

Molecular Weight: 54.7 kDa

UniProt: Q62170