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CTSA Protein (AA 29-480) (His tag)

CTSA Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1945402
  • Target See all CTSA Proteins
    CTSA (Cathepsin A (CTSA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-480
    Origin
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    Human
    Source
    • 12
    • 4
    • 4
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CTSA protein is labelled with His tag.
    Purpose
    Recombinant Human Cathepsin A/CTSA (C-6His)
    Sequence
    APDQDEIQRL PGLAKQPSFR QYSGYLKGSG SKHLHYWFVE SQKDPENSPV VLWLNGGPGC SSLDGLLTEH GPFLVQPDGV TLEYNPYSWN LIANVLYLES PAGVGFSYSD DKFYATNDTE VAQSNFEALQ DFFRLFPEYK NNKLFLTGES YAGIYIPTLA VLVMQDPSMN LQGLAVGNGL SSYEQNDNSL VYFAYYHGLL GNRLWSSLQT HCCSQNKCNF YDNKDLECVT NLQEVARIVG NSGLNIYNLY APCAGGVPSH FRYEKDTVVV QDLGNIFTRL PLKRMWHQAL LRSGDKVRMD PPCTNTTAAS TYLNNPYVRK ALNIPEQLPQ WDMCNFLVNL QYRRLYRSMN SQYLKLLSSQ KYQILLYNGD VDMACNFMGD EWFVDSLNQK MEVQRRPWLV KYGDSGEQIA GFVKEFSHIA FLTIKGAGHM VPTDKPLAAF TMFSRFLNKQ PYHHHHHH
    Characteristics
    Recombinant Human cathepsin A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala29­Tyr480) of Human cathepsin A fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CTSA Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CTSA (Cathepsin A (CTSA))
    Alternative Name
    Cathepsin A (CTSA Products)
    Synonyms
    Ppgb Protein, beta-galactosidase 2 Protein, PPGB Protein, GLB2 Protein, GSL Protein, NGBE Protein, PPCA Protein, AU019505 Protein, cathepsin A Protein, beta-galactosidase 2 Protein, Ctsa Protein, BGAL2 Protein, CTSA Protein
    Background
    Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.
    Molecular Weight
    52.2 kDa
    UniProt
    P10619
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