CTSA Protein (AA 29-480) (His tag)
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- Target See all CTSA Proteins
- CTSA (Cathepsin A (CTSA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-480
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CTSA protein is labelled with His tag.
- Purpose
- Recombinant Human Cathepsin A/CTSA (C-6His)
- Sequence
- APDQDEIQRL PGLAKQPSFR QYSGYLKGSG SKHLHYWFVE SQKDPENSPV VLWLNGGPGC SSLDGLLTEH GPFLVQPDGV TLEYNPYSWN LIANVLYLES PAGVGFSYSD DKFYATNDTE VAQSNFEALQ DFFRLFPEYK NNKLFLTGES YAGIYIPTLA VLVMQDPSMN LQGLAVGNGL SSYEQNDNSL VYFAYYHGLL GNRLWSSLQT HCCSQNKCNF YDNKDLECVT NLQEVARIVG NSGLNIYNLY APCAGGVPSH FRYEKDTVVV QDLGNIFTRL PLKRMWHQAL LRSGDKVRMD PPCTNTTAAS TYLNNPYVRK ALNIPEQLPQ WDMCNFLVNL QYRRLYRSMN SQYLKLLSSQ KYQILLYNGD VDMACNFMGD EWFVDSLNQK MEVQRRPWLV KYGDSGEQIA GFVKEFSHIA FLTIKGAGHM VPTDKPLAAF TMFSRFLNKQ PYHHHHHH
- Characteristics
- Recombinant Human cathepsin A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala29Tyr480) of Human cathepsin A fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CTSA Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- CTSA (Cathepsin A (CTSA))
- Alternative Name
- Cathepsin A (CTSA Products)
- Synonyms
- Ppgb Protein, beta-galactosidase 2 Protein, PPGB Protein, GLB2 Protein, GSL Protein, NGBE Protein, PPCA Protein, AU019505 Protein, cathepsin A Protein, beta-galactosidase 2 Protein, Ctsa Protein, BGAL2 Protein, CTSA Protein
- Background
- Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.
- Molecular Weight
- 52.2 kDa
- UniProt
- P10619
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