INPP5A Protein (AA 1-410) (His tag)
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- Target See all INPP5A Proteins
- INPP5A (Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-410
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This INPP5A protein is labelled with His tag.
- Purpose
- Recombinant Human Type I Inositol 1,4,5-Trisphosphate 5-Phosphatase/INPP5A (C-6His)
- Sequence
- MAGKAAAPGT AVLLVTANVG SLFDDPENLQ KNWLREFYQV VHTHKPHFMA LHCQEFGGKN YEASMSHVDK FVKELLSSDA MKEYNRARVY LDENYKSQEH FTALGSFYFL HESLKNIYQF DFKAKKYRKV AGKEIYSDTL ESTPMLEKEK FPQDYFPECK WSRKGFIRTR WCIADCAFDL VNIHLFHDAS NLVAWETSPS VYSGIRHKAL GYVLDRIIDQ RFEKVSYFVF GDFNFRLDSK SVVETLCTKA TMQTVRAADT NEVVKLIFRE SDNDRKVMLQ LEKKLFDYFN QEVFRDNNGT ALLEFDKELS VFKDRLYELD ISFPPSYPYS EDARQGEQYM NTRCPAWCDR ILMSPSAKEL VLRSESEEKV VTYDHIGPNV CMGDHKPVFL AFRIMPGAGK PHAHVHKCCV DHHHHHH
- Characteristics
- Recombinant Human INPP5A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 1-410) of Human INPP5A fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product INPP5A Protein
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Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A) (AA 1-412) protein (GST tag)
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Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A) (AA 1-409) protein (His tag)Crystallography grade INPP5A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A) (AA 1-409), (full length) protein (His-SUMO Tag)INPP5A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A) protein (Myc-DYKDDDDK Tag)INPP5A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- INPP5A (Inositol Polyphosphate-5-Phosphatase, 40kDa (INPP5A))
- Alternative Name
- INPP5A (INPP5A Products)
- Synonyms
- 5PTASE Protein, inositol polyphosphate-5-phosphatase A Protein, INPP5A Protein
- Background
- Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
- Molecular Weight
- 48.5 kDa
- UniProt
- Q14642
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