Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 1-225) (Active) Protein

Details for Product No. ABIN1981664, Supplier: Log in to see
Protein Name
  • GST5
  • GSTB
  • GSTM3-3
  • GTM3
  • Fsc2
  • mGSTM5
  • glutathione S-transferase mu 3
  • glutathione S-transferase Mu 3
  • glutathione S-transferase, mu 3
  • GSTM3
  • Gstm3
  • LOC479911
Protein Characteristics
AA 1-225
1
1
1
1
1
Origin
Human
6
1
Source
Escherichia coli (E. coli)
5
1
1
Protein Type
Recombinant
Biological Activity
Active
Application
SDS-PAGE (SDS)
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Sequence MGSSHHHHHH SSGLVPRGSH MGSHMSCESS MVLGYWDIRG LAHAIRLLLE FTDTSYEEKR YTCGEAPDYD RSQWLDVKFK LDLDFPNLPY LLDGKNKITQ SNAILRYIAR KHNMCGETEE EKIRVDIIEN QVMDFRTQLI RLCYSSDHEK LKPQYLEELP GQLKQFSMFL GKFSWFAGEK LTFVDFLTYD ILDQNRIFDP KCLDEFPNLK AFMCRFEALE KIAAYLQSDQ FCKMPINNKM AQWGNKPVC
Characteristics Molecule Information: 29.1 kDa (249 aa, 1-225 aa)
Purity ≥95 % by SDS-PAGE
Biological Activity Comment Specific activity > 4.7 units/mg, one unit is defined as the amount of enzyme that conjugate 1.0 μmole of 1-chloro-2, 4-dinitrobenzene (CDNB), with reduced glutathione per minute pH 6.5 at 25°C.
Unit Definition One unit is defined as the amount of enzyme that conjugate 1.0 μmole of 1-chloro-2, 4-dinitrobenzene (CDNB), with reduced glutathione per minute pH 6.5 at 25°C.
Protein Name
Background Glutathione S-transferase mu 3, also known as GSTM3, is member of the glutathione s-transferase (GST) family of proteins. There are eight families of GST proteins, namely alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have a variety of functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Recombinant human GSTM3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternative Names: Glutathione S-transferase mu 3, GST5, GSTB, GSTM3-3, GTM3
Molecular Weight 29.1 kDa
Gene ID 2947
UniProt P21266
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 1 mg/mL solution 20 mM Tris-HCl buffer, pH 8.0, 10 % glycerol, 1 mM DTT and 100 mM NaCl.
Preservative Dithiothreitol (DTT)
Precaution of Use This product contains dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Centrifuge the vial prior to opening.
Storage -20 °C
Expiry Date 12 months
Supplier Images
SDS-PAGE (SDS) image for Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 1-225) (Active) protein (ABIN1981664) Glutathione S-Transferase mu 3 (Brain) (GSTM3) (AA 1-225) (Active) protein
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