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Pepsinogen 4, Group I (Pepsinogen A) (PGA4) (AA 1-388) (Active) protein (Fc Tag) Protein

PGA4 Origin: Human Source: Human Cells Recombinant > 80 % as determined by SDS-PAGE Func, SDS
Catalog No. ABIN2005411
$285.35
Plus shipping costs $45.00
10 μg ABIN2005411
10 μg ABIN2005411
local_shipping Shipping to: United States
Delivery in 14 to 16 Business Days
  • Protein Name
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 1-388
    Origin
    Human
    Source
    Human Cells
    Purification tag / Conjugate
    This PGA4 protein is labelled with Fc Tag.
    Application
    Functional Studies (Func), SDS-PAGE (SDS)
    Characteristics
    The secreted recombinant human PGA4/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 614 amino acids and has a predicted molecular mass of 67.3 kDa. The apparent molecular mass of rhPGA/Fc monomer is approximately 65-70 kDa in SDS-PAGE under reducing conditions.

    Protein Structure: A DNA sequence encoding the human PGA4 (P00790) (Met 1-Ala 388) was fused with the Fc region of human IgG1 at the C-terminus.
    Predicted N-Term: Ile 16
    Purity
    > 80 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Biological Activity Comment
    Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2, AnaSpec, Catalog # 27114.
    The specific activity is > 3000 pmoles/min/μg.
    (Activation description: The enzyme achieves its activity under acidic pH)
  • Protein Name
    Background
    Synonyms: FLJ58952,FLJ77962,PGA3,PGA4,PGA5
    Molecular Weight
    67.3 kDa, 65-70 kDa
    UniProt
    P00790
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Handling Advice
    Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

    Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
    Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
    Expiry Date
    12 months
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