FK506 Binding Protein 7 (FKBP7) (AA 1-218) protein (Fc Tag)

Details for Product No. ABIN2005613, Supplier: Log in to see
Protein Name
  • FKBP
  • si:dz167c3.2
  • FKBP-7
  • DKFZp469I2124
  • FKBP23
  • PPIase
  • 23kDa
  • FK506 binding protein 7
  • FK506 binding protein 7 L homeolog
  • fkbp7
  • FKBP7
  • fkbp7.L
  • Fkbp7
Protein Characteristics
AA 1-218
2
1
1
1
1
1
1
1
1
1
1
Origin
Human
9
3
Source
Human Cells
4
3
2
2
1
Protein Type
Recombinant
Purification tag / Conjugate
Fc Tag
Application
SDS-PAGE (SDS)
Options
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Characteristics The recombinant human FKBP7/Fc is a disulfide-linked homodimer. The reduced monomer comprises 436 amino acids and has a predicted molecular mass of 49.4 kDa. The apparent molecular mass of the protein is approximately 55 kDa in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the human FKBP7 (Q9Y680-2) (Met1-Gln218) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Predicted N-Term: Gln 24
Purity > 90 % as determined by SDS-PAGE
Endotoxin Level < 1.0 EU per μg of the protein as determined by the LAL method
Protein Name
Background Synonyms: FKBP23,PPIase
Molecular Weight 49.4 kDa
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handling Advice Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Storage -20 °C,-80 °C
Storage Comment Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Expiry Date 12 months
Supplier Images
 image for FK506 Binding Protein 7 (FKBP7) (AA 1-218) protein (Fc Tag) (ABIN2005613) FK506 Binding Protein 7 (FKBP7) (AA 1-218) protein (Fc Tag)
Background publications Shor, Zhang, Toral-Barza, Lucas, Abraham, Gibbons, Yu: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, 2008

Shor, Zhang, Toral-Barza, Lucas, Abraham, Gibbons, Yu: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, 2008 (PubMed).

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