Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-53) (Active) protein (Fc Tag)

Details for Product No. ABIN2009845, Supplier: Log in to see
Protein Name
  • TNFRSF17
  • BCM
  • BCMA
  • CD269
  • TNFRSF13A
  • Tnfrsf13
  • Tnfrsf13a
  • TNF receptor superfamily member 17
  • tumor necrosis factor receptor superfamily, member 17
  • Tnfrsf17
  • TNFRSF17
Protein Characteristics
AA 1-53
14
8
7
4
3
2
2
2
2
1
1
1
1
Origin
Rhesus Monkey
47
18
6
6
1
Source
Human Cells
26
20
11
3
2
2
1
Protein Type
Recombinant
Biological Activity
Active
Purification tag / Conjugate
This TNFRSF17 protein is labelled with Fc Tag.
Application
Functional Studies (Func), SDS-PAGE (SDS)
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Characteristics The recombinant rhesus TNFRSF17 comprises 294 amino acids and has a calculated molecular mass of 33 KDa.

Protein Structure: A DNA sequence encoding the rhesus TNFRSF17 (XP_001106892.1) (Met1-Ala53) was expressed with the Fc region of human IgG1 at the C-terminus.
Predicted N-Term: Met
Purity > 95 % as determined by SDS-PAGE
Endotoxin Level < 1.0 EU per μg of the protein as determined by the LAL method
Biological Activity Comment Measured by its binding ability in a functional ELISA. Immobilized human BAFF at 10 μg/ml (100 μl/well) can bind Rhesus TNFRSF17-Fc, The EC50 of Rhesus TNFRSF17-Fc is 0.03-0.07 μg/mL.
Protein Name
NCBI Accession XP_001106892
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handling Advice Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Storage -20 °C,-80 °C
Storage Comment Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Expiry Date 12 months
Supplier Images
 image for Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-53) (Active) protein (Fc Tag) (ABIN2009845) Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-53) (Active) protein (Fc Tag)
Background publications Hymowitz, Patel, Wallweber, Runyon, Yan, Yin, Shriver, Gordon, Pan, Skelton, Kelley, Starovasnik: "Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 7218-27, 2005 (PubMed).

Liu, Hong, Kappler, Jiang, Zhang, Xu, Pan, Martin, Murphy, Shu, Dai, Zhang: "Ligand-receptor binding revealed by the TNF family member TALL-1." in: Nature, Vol. 423, Issue 6935, pp. 49-56, 2003 (PubMed).

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