Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 24-99) (Active) Protein

Details for Product No. ABIN2017721
Protein Name
Protein Characteristics
AA 24-99
6
2
1
1
1
1
1
1
1
Origin
Human
35
3
1
Source
Escherichia coli (E. coli)
25
5
2
2
1
1
Protein Type
Recombinant
Biological Activity
Active
Options
Characteristics The EC50 value of human Ck beta 8-1/CCL23 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 0.4 μg/mL.
Purity > 98 % as analyzed by SDS-PAGE.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Protein Name
Background Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family that is also known as Macrophage inflammatory protein 3 (MIP-3) and Myeloid progenitor inhibitory factor 1 (MPIF-1). CCL23 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta.CCL23 is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. CCL23 is a ligand for the chemokine receptor CCR1.Recombinant human Ck beta 8-1/CCL23 produced in CHO cells is a single polypeptide chain containing 92 amino acids. A fully biologically active molecule, rhCk beta 8-1/CCL23 has a molecular mass of 10.5 kDa analyzed by reducing SDS-PAGE.
Synonyms: Ckbeta 8-1/CCL23, Human
Molecular Weight 10.5 kDa, observed by reducing SDS-PAGE.
UniProt P80075
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/mL.
Buffer Lyophilized after extensive dialysis against PBS.
Storage -80 °C
Storage Comment Lyophilized recombinant human Ck beta 8-1/CCL23 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human Ck beta 8-1/CCL23 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
Expiry Date 6 months