IFNGR2 Protein (AA 28-247)
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- Target See all IFNGR2 Proteins
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 28-247
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Origin
- Human
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Source
- CHO Cells
- Characteristics
- ED50 < 0.1 μg/mL, measured in a cell cytotoxicity assay using HT-29 (HTB-38) cells in the presence of 1 ng/mL human IFN-gamma.
- Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IFNGR2 Protein
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Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) (AA 28-127) protein (GST tag)
IFNGR2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) (AA 1-337) protein (GST tag)IFNGR2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) protein (His tag)IFNGR2 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) (AA 28-247) protein (His tag)Crystallography grade IFNGR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) (AA 22-337) protein (rho-1D4 tag)Crystallography grade IFNGR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2) protein (Myc-DYKDDDDK Tag)IFNGR2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Human IFN-gamma Receptor II remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human IFN-gamma Receptor II should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- Abstract
- IFNGR2 Products
- Synonyms
- Ifgr2 Protein, Ifgt Protein, AF-1 Protein, IFGR2 Protein, IFNGT1 Protein, interferon gamma receptor 2 Protein, Ifngr2 Protein, IFNGR2 Protein, LOC487739 Protein
- Background
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IFN-gamma Receptor II, also known as IFNGR2 and IFNGT1, is a transmembrane protein belonging to the type II cytokine receptor family. IFNGR2 is a non-ligand-binding beta chain of the IFN-gamma receptor. It is an integral part of the IFN-gamma signaling transduction pathway and is likely to interact with GAF, JAK1 and JAK2. Defects in IFNGR2 are a cause of autosomal recessive Mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
Synonyms: IFNGR2, IFNGT1 - Molecular Weight
- 38-40 kDa, observed by reducing SDS-PAGE.
- UniProt
- P38484
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