IGFBP2 Protein (AA 40-325) (His tag)

Catalog No. ABIN2017975

Product Details

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 40-325

Origin: Human

Source: HEK-293T Cells

Purification tag / Conjugate: This IGFBP2 protein is labelled with His tag.

Characteristics: ED50 < 2 μg/mL, measured in a bioassay using FDC-P1 cells in the presence of 15 ng/mL human IGF-II.
AA 40-325, expressed with C-terminal 6xHis.

Purity: > 95 % as analyzed by SDS-PAGE.

Endotoxin Level: < 0.2 EU/μg, determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Storage: -80 °C

Storage Comment: Lyophilized recombinant human IGF-BP-2, Hisremains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human IGF-BP-2, His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Expiry Date: 6 months

Target Details

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Abstract: IGFBP2 Products

Synonyms: IBP2 Protein, IGF-BP53 Protein, AI255832 Protein, IBP-2 Protein, Igfbp-2 Protein, mIGFBP-2 Protein, IGFBP-2 Protein, ILGFBPA Protein, pIGFBP-2 Protein, igfbp2 Protein, MGC65741 Protein, MGC76823 Protein, MGC174445 Protein, IGFBP2 Protein, ibp2 Protein, igf-bp53 Protein, igfbp2a Protein, si:ch211-2k18.3 Protein, insulin like growth factor binding protein 2 Protein, insulin-like growth factor binding protein 2 Protein, insulin-like growth factor binding protein 2a Protein, insulin-like growth factor binding protein 2b Protein, IGFBP2 Protein, Igfbp2 Protein, igfbp2a Protein, igfbp2 Protein, igfbp2b Protein

Background: IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
Synonyms: Insulin-like growth factor-binding protein 2, IBP-2, BP-2

Molecular Weight: 6-20 kDa, observed by reducing SDS-PAGE.

UniProt: P18065

Pathways: Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation