SERPINA10 Protein (AA 22-444) (His tag)

Catalog No. ABIN2115434

Product Details

Target: SERPINA10 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 10 (SERPINA10))

Protein Type: Recombinant

Protein Characteristics: AA 22-444

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This SERPINA10 protein is labelled with His tag.

Purpose: Recombinant Human Serpin A10/ZPI (C-6His)

Sequence: LAPSPQSPET PAPQNQTSRV VQAPKEEEED EQEASEEKAS EEEKAWLMAS RQQLAKETSN FGFSLLRKIS MRHDGNMVFS PFGMSLAMTG LMLGATGPTE TQIKRGLHLQ ALKPTKPGLL PSLFKGLRET LSRNLELGLT QGSFAFIHKD FDVKETFFNL SKRYFDTECV PMNFRNASQA KRLMNHYINK ETRGKIPKLF DEINPETKLI LVDYILFKGK WLTPFDPVFT EVDTFHLDKY KTIKVPMMYG AGKFASTFDK NFRCHVLKLP YQGNATMLVV LMEKMGDHLA LEDYLTTDLV ETWLRNMKTR NMEVFFPKFK LDQKYEMHEL LRQMGIRRIF SPFADLSELS ATGRNLQVSR VLQRTVIEVD ERGTEAVAGI LSEITAYSMP PVIKVDRPFH FMIYEETSGM LLFLGRVVNP TLLLDHHHHH H

Characteristics: Recombinant Human Serpin A10 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu22-Leu444) of Human SERPINA10 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,1 mM GaCl2, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SERPINA10 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 10 (SERPINA10))

Alternative Name: Serpin A10 (SERPINA10 Products)

Synonyms: PZI Protein, ZPI Protein, Rasp1 Protein, SERPINA10 Protein, DKFZp469K045 Protein, si:dkey-85n7.5 Protein, serpin family A member 10 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 Protein, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a Protein, SERPINA10 Protein, Serpina10 Protein, serpina10a Protein

Background: Serpin A10 is a secreted protein that belongs to the serpin family. It is predominantly expressed in the liver and secreted in the plasma. Its phosphorylation sites are present in the extracelllular medium. It inhibits factors Xa and XIa of the coagulation cascade in the presence of protein Z, calcium, and phospholipid. Mutations in SERPINA10 are associated with venous thrombosis.
Synonyms: Protein Z-Dependent Protease Inhibitor, PZ-Fependent Protease Inhibitor, PZI, Serpin A10, SERPINA10, ZPI

Molecular Weight: 49.5 kDa

UniProt: Q9UK55