Dermatopontin Protein (DPT) (AA 19-201) (Fc Tag,His tag)

Catalog No. ABIN2115437

Product Details

Target: Dermatopontin (DPT)

Protein Type: Recombinant

Protein Characteristics: AA 19-201

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Dermatopontin protein is labelled with Fc Tag,His tag.

Purpose: Recombinant Human Dermatopontin/DPT/TRAMP (C-Fc-6His)

Sequence: QYGDYGYPYQ QYHDYSDDGW VNLNRQGFSY QCPQGQVIVA VRSIFSKKEG SDRQWNYACM PTPQSLGEPT ECWWEEINRA GMEWYQTCSN NGLVAGFQSR YFESVLDREW QFYCCRYSKR CPYSCWLTIE YPGHYGEEMD MISYNYDYYI RGATTTFSAV ERDRQWKFIM CRMTEYDCEF ANVVDDIEGR MDEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH

Characteristics: Recombinant Human Dermatopontin/DPT is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln19-Val201) of Human Dermatopontin fused with a FC-6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Dermatopontin (DPT)

Alternative Name: Dermatopontin (DPT Products)

Synonyms: MGC108277 Protein, TRAMP Protein, 1810032B19Rik Protein, 5033416F05Rik Protein, EQ-1 Protein, Eq1 Protein, dermatopontin Protein, DPT Protein, dpt Protein, Dpt Protein

Background: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.
Synonyms: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT,

Molecular Weight: 49.9 kDa

UniProt: Q07507