HCV NS4 Genotype 1 Protein (AA 1691-1710, AA 1712-1733, AA 1921-1940) (GST tag)
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- Target
- HCV NS4 Genotype 1 (HCV NS4) (Hepatitis C Virus NS4 Mosaic Genotype-1 (HCV NS4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1691-1710, AA 1712-1733, AA 1921-1940
- Origin
- Hepatitis C Virus (HCV)
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HCV NS4 Genotype 1 protein is labelled with GST tag.
- Application
- ELISA, Western Blotting (WB)
- Characteristics
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Hepatitis C Virus NS4 Mosaic Genotype-1 recombinant protein
Expression System: E.coli - Purification
- Proprietary chromatographic technique
- Purity
- > 95 % pure
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 1.5 M urea, with 25 mM Tris-HCl, pH -8, 0.2 % Triton-X and 52 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- HCV NS4 Genotype 1 (HCV NS4) (Hepatitis C Virus NS4 Mosaic Genotype-1 (HCV NS4))
- Target Type
- Viral Protein
- Background
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HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Alternative Names: Hepatitis C protein, HCV protein, Hep C protein, HCV Recombinant protein, HCV NS4 Genotype 1 protein
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