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DLL4 Protein (AA 27-524) (His tag)

DLL4 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN2180971
  • Target See all DLL4 Proteins
    DLL4 (delta-Like 4 (DLL4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-524
    Origin
    • 13
    • 5
    • 3
    Human
    Source
    • 9
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DLL4 protein is labelled with His tag.
    Sequence
    AA 27-524
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.1 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >90 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product DLL4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    DLL4 (delta-Like 4 (DLL4))
    Alternative Name
    DLL4 (DLL4 Products)
    Background
    Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
    Molecular Weight
    55.5 kDa
    Pathways
    Notch Signaling
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