DLL4 Protein (AA 27-524) (His tag)
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- Target See all DLL4 Proteins
- DLL4 (delta-Like 4 (DLL4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-524
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DLL4 protein is labelled with His tag.
- Sequence
- AA 27-524
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.1 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >90 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product DLL4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- DLL4 (delta-Like 4 (DLL4))
- Alternative Name
- DLL4 (DLL4 Products)
- Background
- Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
- Molecular Weight
- 55.5 kDa
- Pathways
- Notch Signaling
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