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DLL4 Protein (AA 27-524) (Fc Tag)

DLL4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2180973
  • Target See all DLL4 Proteins
    DLL4 (delta-Like 4 (DLL4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-524
    Origin
    • 13
    • 5
    • 3
    Human
    Source
    • 9
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DLL4 protein is labelled with Fc Tag.
    Sequence
    AA 27-524
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 81 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product DLL4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    DLL4 (delta-Like 4 (DLL4))
    Alternative Name
    DLL4 (DLL4 Products)
    Synonyms
    hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
    Background
    Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4). DLL4 contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 plays a role in the Notch signaling pathway. DLL4 activates Notch-1 and Notch-4.
    Molecular Weight
    80.9 kDa
    NCBI Accession
    NP_061947
    Pathways
    Notch Signaling
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