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Ephrin A3 Protein (EFNA3) (AA 23-213) (Fc Tag)

EFNA3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181027
  • Target See all Ephrin A3 (EFNA3) Proteins
    Ephrin A3 (EFNA3)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-213
    Origin
    • 10
    • 2
    • 2
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Ephrin A3 protein is labelled with Fc Tag.
    Sequence
    AA 23-213
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product EFNA3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    Ephrin A3 (EFNA3)
    Alternative Name
    Ephrin-A3 (EFNA3 Products)
    Synonyms
    efna3 Protein, D160 Protein, ephrin-A3 Protein, zgc:100772 Protein, AW494418 Protein, EFL-2 Protein, Ehk1-L Protein, Epl3 Protein, LERK-3 Protein, MGC64593 Protein, EFL2 Protein, EPLG3 Protein, LERK3 Protein, ephrin A3 Protein, ephrin-A3b Protein, ephrin A3 L homeolog Protein, efna3 Protein, EFNA3 Protein, efna3b Protein, Efna3 Protein, efna3.L Protein
    Background
    Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.
    Molecular Weight
    48 kDa
    Pathways
    RTK Signaling
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