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WFDC2 Protein (AA 31-124) (His tag)

WFDC2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181198
  • Target See all WFDC2 Proteins
    WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 31-124
    Origin
    • 10
    • 2
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This WFDC2 protein is labelled with His tag.
    Sequence
    AA 31-124
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.9 kDa. The protein migrates as 19 kDa and 22-26 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product WFDC2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Yang, Lu, Guo, Fellman, Ning, Lu, Menon, Kobayashi, Hanash, Celestino, Skates, Bast: "Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer." in: Cancer, (2019) (PubMed).

  • Target
    WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
    Alternative Name
    HE4 (WFDC2 Products)
    Synonyms
    WFDC3 Protein, WFDC2 Protein, si:ch211-153a8.3 Protein, EDDM4 Protein, HE4 Protein, WAP5 Protein, dJ461P17.6 Protein, 1600023A02Rik Protein, re4 Protein, CE4 Protein, BE-20 Protein, WAP four-disulfide core domain 2 Protein, WFDC2 Protein, wfdc2 Protein, Wfdc2 Protein
    Background
    Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.
    Molecular Weight
    10.9 kDa
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