MMP 9 Protein (AA 20-469) (His tag)
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- Target See all MMP 9 (MMP9) Proteins
- MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-469
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MMP 9 protein is labelled with His tag.
- Sequence
- AA 20-469
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.8 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MMP9 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
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- Target
- MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
- Alternative Name
- MMP-9 (MMP9 Products)
- Synonyms
- CLG4B Protein, GELB Protein, MANDP2 Protein, MMP-9 Protein, AW743869 Protein, B/MMP9 Protein, Clg4b Protein, pro-MMP-9 Protein, mmp-9 Protein, fgMMP-9 Protein, mmp9 Protein, ZFMMP-9 Protein, wu:fb02g06 Protein, wu:fb07b05 Protein, wu:fi98c09 Protein, wu:fj05a08 Protein, zgc:64165 Protein, clg4b Protein, gelb Protein, mandp2 Protein, matrix metallopeptidase 9 Protein, collagenase Protein, matrix metalloproteinase 9 Protein, matrix metallopeptidase 9 S homeolog Protein, MMP9 Protein, RB3913 Protein, BPSS0666 Protein, Sbal_3732 Protein, Bcer98_0486 Protein, Shew185_0630 Protein, Shal_3056 Protein, Sbal195_0657 Protein, Lbys_3550 Protein, Palpr_2084 Protein, Mmp9 Protein, mmp9 Protein, mmp9.S Protein
- Background
- Matrix metallopeptidase 9 (MMP-9) is also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), CLG4B, is secreted from neutrophils, macrophages, and a number of transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. . Structurally, MMP9 maybe be divided into five distinct domains: a prodomain which is cleaved upon activation, a gelatinbinding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a prolinerich linker region, and a carboxyl terminal hemopexinlike domain. This enzyme degrades various substrates including gelatin, collagen types IV and V, and elastin. MMP9 is involved in a variety of autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis, and be regarded as a potential therapeutic target.
- Molecular Weight
- 50.8 kDa
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events
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