NCR3 Protein (AA 19-135) (Fc Tag)
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- Target See all NCR3 Proteins
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-135
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NCR3 protein is labelled with Fc Tag.
- Sequence
- AA 19-135
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.5 kDa. As a result of glycosylation, the protein migrates as 45-55 kDa under reducing (R) condition, and 90-110 kDa under non-reducing (NR) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NCR3 Protein
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Natural Cytotoxicity Triggering Receptor 3 (NCR3) protein (His-Avi Tag)
NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
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Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (His-Avi Tag,Biotin)NCR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (His-DYKDDDDK-Strep II Tag)NCR3 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 1-201) protein (GST tag)NCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (His tag)Crystallography grade NCR3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-201) protein (rho-1D4 tag)Crystallography grade NCR3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- Alternative Name
- NKp30 (NCR3 Products)
- Synonyms
- MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
- Background
- Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
- Molecular Weight
- 39.5 kDa
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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