S100A10 Protein (AA 1-97) (His tag)

Catalog No. ABIN2181711

Product Details

Target: S100A10 (S100 Calcium Binding Protein A10 (S100A10))

Protein Type: Recombinant

Protein Characteristics: AA 1-97

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This S100A10 protein is labelled with His tag.

Sequence: AA 1-97

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).

Purity: >95 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 150 mM NaCl, pH 8.0

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Target Details

Target: S100A10 (S100 Calcium Binding Protein A10 (S100A10))

Alternative Name: S100A10 (S100A10 Products)

Synonyms: 42C Protein, ANX2L Protein, ANX2LG Protein, CAL1L Protein, CLP11 Protein, Ca[1] Protein, GP11 Protein, P11 Protein, p10 Protein, AA409961 Protein, AL024248 Protein, CAL12 Protein, Cal1l Protein, p11 Protein, s100a10 Protein, 42c Protein, anx2l Protein, anx2lg Protein, cal1l Protein, calpactin Protein, clp11 Protein, gp11 Protein, p11-A Protein, s100a10b Protein, hm:zehn1116 Protein, wu:fa94d11 Protein, wu:fb05h04 Protein, zgc:56142 Protein, zgc:101880 Protein, S100 calcium binding protein A10 Protein, S100 calcium binding protein A10 (calpactin) Protein, S100 calcium binding protein A10 L homeolog Protein, S100 calcium binding protein A10b Protein, S100 calcium binding protein A10a Protein, S100A10 Protein, S100a10 Protein, s100a10 Protein, s100a10.L Protein, s100a10b Protein, s100a10a Protein

Background: S100 calcium-binding protein A10 (S100A10), a member of the S100 family of proteins containing two EF-hand calcium-binding motifs, is also known as protein S100-A10, calpactin I light chain, cellular ligand of annexin II, p10 protein and p11, which can be found as a free monomer, a homodimer, or a heterotetramer composed of a p11 dimer complex with two molecules of annexin II. S100A10 is an integral part of cellular structural scaffolding that interacts with plasma membrane proteins through its association with annexin II. S100A10 also works together with cytosolic and peripheral membrane-associated proteins such as AHNAK in the development of the intracellular membrane. Furthermore,S100A10 has been implicated in the transportation of proteins involved in mood regulation, nociception, and cell polarization. Complexed with the annexin II, S100A10 binds receptor and channel proteins and guides them to the cell surface, resulting in increased membrane localization and consequent magnified functional expression of these proteins.

Molecular Weight: 12.0 kDa

Pathways: S100 Proteins