SIGLEC6 Protein (AA 16-320) (Fc Tag)
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- Target See all SIGLEC6 Proteins
- SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 16-320
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIGLEC6 protein is labelled with Fc Tag.
- Sequence
- AA 16-320
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.3 kDa. As a result of glycosylation, the protein migrates as 80-90 kDa under reducing (R) condition, and 160-180 kDa under non-reducing (NR) condition (SDS-PAGE).
- Purity
- >90 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SIGLEC6 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
- Alternative Name
- Siglec-6 (SIGLEC6 Products)
- Synonyms
- SIGLEC6 Protein, CD327 Protein, CD33L Protein, CD33L1 Protein, CD33L2 Protein, CDW327 Protein, OBBP1 Protein, sialic acid binding Ig like lectin 6 Protein, SIGLEC6 Protein
- Background
- Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
- Molecular Weight
- 60.3 kDa
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