TTR Protein (AA 21-147) (His tag)
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- Target See all TTR Proteins
- TTR (Transthyretin (TTR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-147
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TTR protein is labelled with His tag.
- Sequence
- AA 21-147
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.6 kDa. The protein migrates as 19 kDa and 37 kDa under reducing (R) condition (SDS-PAGE) due to the monomer and dimer respectively.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TTR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- TTR (Transthyretin (TTR))
- Alternative Name
- Transthyretin (TTR Products)
- Synonyms
- zgc:103583 Protein, TTR Protein, LOC100226992 Protein, CTS Protein, CTS1 Protein, HsT2651 Protein, PALB Protein, TBPA Protein, AA408768 Protein, AI787086 Protein, D17860 Protein, prealbumin Protein, Lr1 Protein, Tbpa Protein, Prealbumin Protein, xTTR Protein, transthyretin (prealbumin, amyloidosis type I) Protein, transthyretin Protein, Transthyretin Protein, transthyretin (prealbumin, amyloidosis type 1) Protein, transthyretin-like Protein, transthyretin L homeolog Protein, ttr Protein, TTR Protein, vpb38 Protein, MRAD2831_RS38185 Protein, Caci_4246 Protein, LOC100226992 Protein, Ttr Protein, ttr.L Protein
- Background
- Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family. Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1 % of TTR's T4 binding sites are occupied in blood. TTR misfolding and aggregation is known to be associated with the amyloid diseases.
- Molecular Weight
- 14.9 kDa
- NCBI Accession
- NP_000362
- Pathways
- Hormone Transport
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