COL18A1 Protein
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- Target See all COL18A1 Proteins
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK
- Purity
- < 98 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product COL18A1 Protein
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Collagen, Type XVIII, alpha 1 (COL18A1) protein (His tag)
COL18A1 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1572-1754) protein (His tag)Crystallography grade COL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1591-1774) protein (His tag)Crystallography grade COL18A1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Collagen, Type XVIII, alpha 1 (COL18A1) protein (KLH)COL18A1 Origin: Human Host: Synthetic > 95 % SDS, WB, ELISA, IP
Collagen, Type XVIII, alpha 1 (COL18A1) (Transcript Variant 2) (Active) proteinCOL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1578-1754) protein (GST tag)COL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1578-1754) protein (His tag)COL18A1 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing Endostatin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Endostatin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
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- Target
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Alternative Name
- Endostatin (COL18A1 Products)
- Synonyms
- KNO Protein, KNO1 Protein, KS Protein, cb371 Protein, cb529 Protein, fc96d06 Protein, sb:cb529 Protein, wu:fb47h10 Protein, wu:fb77g12 Protein, wu:fc50f04 Protein, wu:fc96d06 Protein, wu:fk02h12 Protein, kno Protein, kno1 Protein, collagen type XVIII alpha 1 chain Protein, collagen type XVIII alpha 1 chain a Protein, collagen, type XVIII, alpha 1 Protein, collagen type XVIII alpha 1 Protein, COL18A1 Protein, col18a1a Protein, Col18a1 Protein, col18a1 Protein
- Target Type
- Chemical
- Background
- Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
- Gene ID
- 80781
- NCBI Accession
- NP_085059
- OMIM
- 110611235
- UniProt
- P39060
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