Chemokine (C-C Motif) Ligand 12 (Ccl12) (Active) Protein

Details for Product No. ABIN2468804
Protein Name
Origin
Mouse (Murine)
17
Source
Escherichia coli (E. coli)
14
1
1
Protein Type
Recombinant
Biological Activity
Active
Options
Sequence GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG
Characteristics Biological activity was determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0 - 50.0 ng/mL.
Purity < 98 % by SDS-PAGE gel and HPLC analyses.
Endotoxin Level Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
Protein Name
Background The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Gene ID 20293
NCBI Accession NP_035461
OMIM 119226206
UniProt Q62401
Pathways Cellular Response to Molecule of Bacterial Origin
Restrictions For Research Use only
Format Lyophilized
Handling Advice As with any protein, exposing MCP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Storage -20 °C
Storage Comment The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted MCP-5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
Expiry Date 24 months