Ccl12 Protein

Catalog No. ABIN2468804

Product Details

Target: Ccl12 (Chemokine (C-C Motif) Ligand 12 (Ccl12))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: Escherichia coli (E. coli)

Sequence: GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG

Characteristics: Biological activity was determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0 - 50.0 ng/mL.

Purity: < 98 % by SDS-PAGE gel and HPLC analyses.

Endotoxin Level: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Handling Advice: As with any protein, exposing MCP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Storage: -20 °C

Storage Comment: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted MCP-5 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Expiry Date: 24 months

Target Details

Target: Ccl12 (Chemokine (C-C Motif) Ligand 12 (Ccl12))

Alternative Name: MCP-5 (Ccl12 Products)

Synonyms: MCP-5 Protein, Scya12 Protein, chemokine (C-C motif) ligand 12 Protein, Ccl12 Protein

Background: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Gene ID: 20293

NCBI Accession: NP_035461

OMIM: 119226206

UniProt: Q62401

Pathways: Cellular Response to Molecule of Bacterial Origin