Fetuin A Protein (His tag)
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- Target See all Fetuin A (AHSG) Proteins
- Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Fetuin A protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Characteristics
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Measured by its ability to inhibit calcium phosphate precipitation in 100 μL reaction mixture containing 4. 8 mM Calcium chloride, 1. 6 mM Sodium phosphate, with the rhFetuin A concentration curve of 250, 125, 62. 5, 31. 3, 15. 6, 7. 8, 3. 9, 1. 95, 0. 97 and 0. 49 μg/mL. The IC50 value is <45 μg/mL.
- Purity
- >98 % as determined by SDS-PAGE.
- Top Product
- Discover our top product AHSG Protein
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- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 25 mM Tris and 150 mM NaCl, pH 7.5
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))
- Alternative Name
- Fetuin A (AHSG Products)
- Synonyms
- ahs Protein, a2hs Protein, hsga Protein, fetua Protein, wu:fb63g02 Protein, zgc:103687 Protein, AHSG Protein, MGC116429 Protein, A2HS Protein, AHS Protein, FETUA Protein, HSGA Protein, Aa2-066 Protein, pp63 Protein, alpha-2-HS-glycoprotein Protein, alpha 2-HS glycoprotein Protein, alpha-2-HS-glycoprotein 1 Protein, alpha-2-HS-glycoprotein L homeolog Protein, Cphamn1_1981 Protein, AHSG Protein, ahsg Protein, ahsg1 Protein, ahsg.L Protein, Ahsg Protein
- Background
- Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues.
- Molecular Weight
- 38.2 kDa
- Gene ID
- 197
- NCBI Accession
- NP_001613
- UniProt
- P02765
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