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Fetuin A Protein (His tag)

AHSG Origin: Human Host: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. WB Active
Catalog No. ABIN2566576
  • Target See all Fetuin A (AHSG) Proteins
    Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 16
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 20
    • 8
    • 7
    • 5
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Fetuin A protein is labelled with His tag.
    Application
    Western Blotting (WB)
    Characteristics

    Measured by its ability to inhibit calcium phosphate precipitation in 100 μL reaction mixture containing 4. 8 mM Calcium chloride, 1. 6 mM Sodium phosphate, with the rhFetuin A concentration curve of 250, 125, 62. 5, 31. 3, 15. 6, 7. 8, 3. 9, 1. 95, 0. 97 and 0. 49 μg/mL. The IC50 value is <45 μg/mL.

    Purity
    >98 % as determined by SDS-PAGE.
    Top Product
    Discover our top product AHSG Protein
  • Application Notes
    This recombinant protein can be used for WB. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    25 mM Tris and 150 mM NaCl, pH 7.5
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))
    Alternative Name
    Fetuin A (AHSG Products)
    Synonyms
    ahs Protein, a2hs Protein, hsga Protein, fetua Protein, wu:fb63g02 Protein, zgc:103687 Protein, AHSG Protein, MGC116429 Protein, A2HS Protein, AHS Protein, FETUA Protein, HSGA Protein, Aa2-066 Protein, pp63 Protein, alpha-2-HS-glycoprotein Protein, alpha 2-HS glycoprotein Protein, alpha-2-HS-glycoprotein 1 Protein, alpha-2-HS-glycoprotein L homeolog Protein, Cphamn1_1981 Protein, AHSG Protein, ahsg Protein, ahsg1 Protein, ahsg.L Protein, Ahsg Protein
    Background
    Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues.
    Molecular Weight
    38.2 kDa
    Gene ID
    197
    NCBI Accession
    NP_001613
    UniProt
    P02765
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