COMP Protein (His tag)
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- Target See all COMP Proteins
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This COMP protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Characteristics
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Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells, when rhCOMP / Thrombospondin-5 immobilized at 1 μg/well. More than 45 % of ATDC-5 cell adhesion will be induced.
- Purity
- >88 % as determined by SDS-PAGE.
- Top Product
- Discover our top product COMP Protein
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Cartilage Oligomeric Matrix Protein (COMP) (C-Term) protein
COMP Origin: Rat Recombinant > 95 % (SDS-PAGE)
Cartilage Oligomeric Matrix Protein (COMP) (AA 21-757) protein (His tag)Crystallography grade COMP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cartilage Oligomeric Matrix Protein (COMP) (AA 20-755) protein (His tag)Crystallography grade COMP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- Alternative Name
- TSP5 (COMP Products)
- Synonyms
- COMP Protein, EDM1 Protein, EPD1 Protein, MED Protein, PSACH Protein, THBS5 Protein, TSP5 Protein, cartilage oligomeric matrix protein Protein, COMP Protein, sce3551 Protein, CJA_1292 Protein, Comp Protein
- Background
- Cartilage oligomeric matrix protein (COMP) is also known as Thrombospondin-5 (TSP5), EDM1, EPD1, MED, PSACH, THBS5, which belongs to the thrombospondin family. COMP / TSP5 contains 4 EGF-like domains, 1 TSP C-terminal (TSPC) domain, 8 TSP type-3 repeats. Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. COMP may play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. COMP can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Thrombospondin-5 could play a role in the pathogenesis of osteoarthritis. COMP is a marker of cartilage turnover.
- Molecular Weight
- 82 kDa
- Gene ID
- 1311
- UniProt
- P49747
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