c-MYC Protein (His tag)

Catalog No. ABIN2669412

Product Details

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This c-MYC protein is labelled with His tag.

Application: Protein Interaction (PI)

Characteristics: Recombinant c-Myc was expressed in a bacterial system (accession number NM 002467) with an amino terminal polyhistidine tag and purified by an affinity column in combination with FPLC chromatography. The purified recombinant protein is greater than 75 % homogeneous and contains no detectable protease, DNase and RNase activity.

Purification: Purified by an affinity column in combination with FPLC chromatography.

Purity: The purified recombinant protein is greater than 75 % homogeneous and contains no detectable protease, DNase and RNase activity.

Application Details

Application Notes: Recombinant c-Myc protein is suitable for DNA and protein-protein interaction assays. 100 ng are sufficient for DNA-protein and protein-protein interaction studies. The standard curve for TransAM® c-Myc was generated using the range of 5-0.625 ng of protein. The molecular weight of the protein is ~64 kDa. NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided.

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Target Details

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: C-Myc (MYC Products)

Synonyms: MRTL Protein, MYCC Protein, bHLHe39 Protein, c-Myc Protein, CMYC Protein, c-myc Protein, C-MYC Protein, LOC100136746 Protein, ARC Protein, B430311C09Rik Protein, MYC Protein, NOP Protein, Nop30 Protein, RNCMYC Protein, mMyc Protein, AU016757 Protein, Myc2 Protein, Niard Protein, Nird Protein, cmyc Protein, zc-myc Protein, c-myc II Protein, myc-B Protein, myc2 Protein, myc1 Protein, CMyc Protein, zgc:55680 Protein, CG10798 Protein, D-Myc Protein, DM Protein, DMYc Protein, Dm Protein, Dmel\CG10798 Protein, Dmyc Protein, EG:BACN5I9.1 Protein, anon-WO03040301.171 Protein, bHLHe57 Protein, c-MYC Protein, d-myc Protein, dMYC Protein, dMyc Protein, dMyc1 Protein, da Protein, dm Protein, dm/dMyc Protein, dm/myc Protein, dmyc Protein, dmyc1 Protein, l(1)G0139 Protein, l(1)G0354 Protein, l(1)G0359 Protein, myc Protein, MYC proto-oncogene, bHLH transcription factor Protein, v-myc myelocytomatosis viral oncogene homolog Protein, nucleolar protein 3 (apoptosis repressor with CARD domain) Protein, myelocytomatosis oncogene Protein, MYC proto-oncogene, bHLH transcription factor a Protein, MYC proto-oncogene, bHLH transcription factor L homeolog Protein, MYC proto-oncogene, bHLH transcription factor S homeolog Protein, v-myc myelocytomatosis viral oncogene homolog (avian) Protein, MYC proto-oncogene, bHLH transcription factor b Protein, CG10798 gene product from transcript CG10798-RB Protein, MYC Protein, LOC100136746 Protein, Nol3 Protein, Myc Protein, myca Protein, myc.L Protein, myc.S Protein, mycb Protein

Background: C-Myc (Myc) is a sequence specific DNA binding transcription factor that regulates gene expression, especially genes involved in cell division. Myc family members contain a basic Helix-Loop-Helix leucine zipper (bHLHZ) domain. Myc family proteins associated with thousands of genes, especially those involved in cell growth and proliferation. c-Myc serves as an integrator of signal transduction, linking extracellular signals to an acute cellular growth response. Mutations and overexpression of c-Myc are associated with cell proliferation and cancer.

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect