TBK1 Protein (Myc-DYKDDDDK Tag)
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- Target See all TBK1 Proteins
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TBK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TBK1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TBK1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TBK1 (TANK-Binding Kinase 1 (TBK1))
- Alternative Name
- Tbk1 (TBK1 Products)
- Synonyms
- nak Protein, t2k Protein, TBK1 Protein, wu:fk70c05 Protein, zgc:136548 Protein, NAK Protein, T2K Protein, 1200008B05Rik Protein, AI462036 Protein, AW048562 Protein, TANK binding kinase 1 L homeolog Protein, TANK binding kinase 1 Protein, TANK-binding kinase 1 Protein, tbk1.L Protein, TBK1 Protein, tbk1 Protein, Tbk1 Protein
- Background
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
- Molecular Weight
- 83.5 kDa
- NCBI Accession
- NP_037386
- Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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