Tyrosine Hydroxylase Protein (TH) (Transcript Variant 2, Tyr3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712391

Product Details

Target: Tyrosine Hydroxylase (TH)

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2, Tyr3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Tyrosine Hydroxylase protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Tyrosine 3-monooxygenase (TH) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine 3-Monooxygenase (Th) (TH Products)

Synonyms: DYT14 Protein, DYT5b Protein, TYH Protein, The Protein, CG10118 Protein, DH65B Protein, DTH Protein, Dmel\\CG10118 Protein, Pale Protein, Ple Protein, TH Protein, Th Protein, VII Protein, dTH1 Protein, dTH65B Protein, pale/ple Protein, th Protein, dyt14 Protein, dyt5b Protein, tyh Protein, tyrosine hydroxylase Protein, pale Protein, tyrosine 3-monooxygenase Protein, tyrosine hydroxylase S homeolog Protein, TH Protein, Th Protein, ple Protein, th Protein, th.S Protein, LOC100008895 Protein

Background: The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 55.4 kDa

NCBI Accession: NP_000351

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour