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COPS6 Protein (Myc-DYKDDDDK Tag)

COPS6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712495
  • Target See all COPS6 Proteins
    COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This COPS6 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human COPS6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product COPS6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
    Alternative Name
    Cops6 (COPS6 Products)
    Synonyms
    CG6932 Protein, CH6 Protein, Csn6 Protein, Dch6 Protein, Dmel\\CG6932 Protein, zgc:112075 Protein, Sgn3 Protein, VIP/MOV34 Protein, CSN6 Protein, MOV34-34KD Protein, COP9 signalosome subunit 6 Protein, COP-9 SigNalosome subunit Protein, COPS6 Protein, Cops6 Protein, CSN6 Protein, cops6 Protein, csn-6 Protein
    Background
    The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
    Molecular Weight
    36 kDa
    NCBI Accession
    NP_006824
    Pathways
    Cell Division Cycle
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