COPS8 Protein (His tag)
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- Target See all COPS8 Proteins
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This COPS8 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human COPS8 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product COPS8 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Alternative Name
- Cops8 (COPS8 Products)
- Synonyms
- COP9 Protein, CSN8 Protein, SGN8 Protein, csn8 Protein, cops8 Protein, MGC76051 Protein, MGC80215 Protein, DDBDRAFT_0167123 Protein, DDBDRAFT_0233107 Protein, DDB_0167123 Protein, DDB_0233107 Protein, zgc:56319 Protein, zgc:86840 Protein, MGC86182 Protein, 9430009J09Rik Protein, AA408242 Protein, Csn8 Protein, Sgn8 Protein, CONSTITUTIVE PHOTOMORPHOGENIC 9 Protein, COP9 SIGNALOSOME SUBUNIT 8 Protein, DL3095C Protein, EMB143 Protein, EMBRYO DEFECTIVE 143 Protein, FCAALL.131 Protein, FUS7 Protein, FUSCA 7 Protein, FUSCA PROTEIN FUS7 Protein, CG13383 Protein, CG33297 Protein, CG42522 Protein, CH8 Protein, Dch8 Protein, Dmel\\CG42522 Protein, Dmel_CG13383 Protein, l(2)SH1829 Protein, l(2)SH2 1829 Protein, COP9 signalosome subunit 8 Protein, COP9 signalosome subunit 8 S homeolog Protein, COP9 signalosome complex subunit 8 Protein, COP9 signalosome subunit 8 L homeolog Protein, COP9 signalosome, subunit CSN8 Protein, COPS8 Protein, Cops8 Protein, cops8 Protein, cops8.S Protein, CSN8 Protein, csn8 Protein, cops8.L Protein, COP9 Protein
- Background
- The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Molecular Weight
- 23.2 kDa
- NCBI Accession
- NP_006701
- Pathways
- Cell Division Cycle
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