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COQ3 Protein (Myc-DYKDDDDK Tag)

COQ3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712499
  • Target See all COQ3 Proteins
    COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This COQ3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human COQ3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product COQ3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
    Alternative Name
    Coq3 (COQ3 Products)
    Synonyms
    4732433J24 Protein, C77934 Protein, DHHBMT Protein, DHHBMTASE Protein, UG0215E05 Protein, bA9819.1 Protein, ATCOQ3 Protein, EMB3002 Protein, F7F1.13 Protein, F7F1_13 Protein, coenzyme Q 3 Protein, embryo defective 3002 Protein, coenzyme Q3 methyltransferase Protein, coenzyme Q3, methyltransferase Protein, coenzyme Q 3 Protein, Coq3 Protein, COQ3 Protein
    Background
    Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008].
    Molecular Weight
    40.9 kDa
    NCBI Accession
    NP_059117
    Pathways
    Methionine Biosynthetic Process
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